Protein Name sigma non-opioid intracellular receptor 1
Organism Rattus norvegicus
Gene ID 29336
Gene Symbol

Sigmar1

UniProt Q9R0C9 (SGMR1_RAT)
Relationships Total Number of functionally related compound(s) : 245
Total Number of Articles : 260
Description

sigma non-opioid intracellular receptor 1

Gene Summary

Enables G protein-coupled opioid receptor activity. Involved in nervous system development; regulation of postsynapse assembly; and response to alcohol. Is active in glutamatergic synapse. Used to study post-traumatic stress disorder. Human ortholog(s) of this gene implicated in amyotrophic lateral sclerosis type 16 and autosomal recessive distal hereditary motor neuronopathy 2. Orthologous to human SIGMAR1 (sigma non-opioid intracellular receptor 1). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • sigma non-opioid intracellular receptor 1
  • opioid receptor, sigma 1
  • sigma 1-type opioid receptor
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Properties