| Protein Name | Fibroblast growth factor receptor 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 79114 |
| Gene Symbol | Fgfr1 |
| UniProt | Q04589 (FGFR1_RAT), Q63827 (Q63827_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
70
Total Number of Articles : 88 |
Description |
Fibroblast growth factor receptor 1 |
| Gene Summary |
Enables cell adhesion molecule binding activity and signaling receptor binding activity. Involved in several processes, including cellular response to histamine; neuron development; and positive regulation of cell population proliferation. Located in nucleus; perinuclear region of cytoplasm; and plasma membrane. Used to study pulmonary hypertension. Biomarker of several diseases, including ischemia (multiple); mesangial proliferative glomerulonephritis; sciatic neuropathy; vascular dementia; and visual epilepsy. Human ortholog(s) of this gene implicated in several diseases, including Jackson-Weiss syndrome; bone disease (multiple); cleft lip; hematologic cancer (multiple); and hypogonadotropic hypogonadism (multiple). Orthologous to human FGFR1 (fibroblast growth factor receptor 1). [provided by Alliance of Genome Resources, Apr 2022] |
| synonyms |
|
| Properties | |