Protein Name decapping mRNA 2
Organism Homo sapiens
Gene ID 167227
Gene Symbol

DCP2

UniProt Q8IU60 (DCP2_HUMAN)
Relationships Total Number of functionally related compound(s) : 63
Total Number of Articles : 46
Description

decapping mRNA 2

Gene Summary

The protein encoded by this gene is a key component of an mRNA-decapping complex required for degradation of mRNAs, both in normal mRNA turnover, and in nonsense-mediated mRNA decay (NMD). It removes the 7-methyl guanine cap structure from mRNA, prior to its degradation from the 5' end. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

synonyms
  • m7GpppN-mRNA hydrolase
  • DCP2 decapping enzyme homolog
  • hDpc
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Properties