Protein Name thioredoxin interacting protein
Organism Mus musculus
Gene ID 56338
Gene Symbol

Txnip

UniProt Q8BG60 (TXNIP_MOUSE)
Relationships Total Number of functionally related compound(s) : 208
Total Number of Articles : 231
Description

thioredoxin interacting protein

Gene Summary

Enables enzyme inhibitor activity. Acts upstream of or within several processes, including negative regulation of transcription by RNA polymerase II; platelet-derived growth factor receptor signaling pathway; and protein import into nucleus. Located in cytoplasm. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study Reye syndrome and hepatocellular carcinoma. Orthologous to human TXNIP (thioredoxin interacting protein). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • thioredoxin-interacting protein
  • hyperlipidemia 1
  • thioredoxin binding protein-2
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Properties