CPRiL

RIGI

RNA sensor RIG-I

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases which are implicated in a number of cellular processes involving RNA binding and alteration of RNA secondary structure. This gene encodes a protein containing RNA helicase-DEAD box protein motifs and a caspase recruitment domain (CARD). It is involved in viral double-stranded (ds) RNA recognition and the regulation of the antiviral innate immune response. Mutations in this gene are associated with Singleton-Merten syndrome 2. [provided by RefSeq, Aug 2020]

• antiviral innate immune response receptor RIG-I
• ATP-dependent RNA helicase DDX58
• DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DEAD box protein 58
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide
DExD/H-box helicase 58
RNA helicase RIG-I
probable ATP-dependent RNA helicase DDX58
retinoic acid-inducible gene 1 protein
retinoic acid-inducible gene I protein
DDX58
RIG-I
RIG1
RLR-1
SGMRT2