Protein Name aquaporin 4
Organism Rattus norvegicus
Gene ID 25293
Gene Symbol


UniProt P47863 (AQP4_RAT), A0A0H2UHZ1 (A0A0H2UHZ1_RAT)
Relationships Total Number of functionally related compound(s) : 208
Total Number of Articles : 333

aquaporin 4

Gene Summary

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]

  • aquaporin-4
  • mercurial-insensitive water channel
  • AQP-4
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