Protein Name C-C motif chemokine ligand 11
Organism Homo sapiens
Gene ID 6356
Gene Symbol


UniProt P51671 (CCL11_HUMAN), Q6I9T4 (Q6I9T4_HUMAN)
Relationships Total Number of functionally related compound(s) : 347
Total Number of Articles : 385

C-C motif chemokine ligand 11

Gene Summary

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014]

  • eotaxin
  • chemokine (C-C motif) ligand 11
  • eosinophil chemotactic protein
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