| Protein Name | C-C motif chemokine ligand 11 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6356 |
| Gene Symbol | CCL11 |
| UniProt | P51671 (CCL11_HUMAN), Q6I9T4 (Q6I9T4_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
347
Total Number of Articles : 385 |
Description |
C-C motif chemokine ligand 11 |
| Gene Summary |
This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, displays chemotactic activity for eosinophils, but not mononuclear cells or neutrophils. This eosinophil-specific chemokine is thought to be involved in eosinophilic inflammatory diseases such as atopic dermatitis, allergic rhinitis, asthma and parasitic infections. [provided by RefSeq, Sep 2014] |
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