| Protein Name | Amyloid-beta-like protein |
|---|---|
| Organism | Caenorhabditis elegans |
| Gene ID | 180783 |
| Gene Symbol | apl-1 |
| UniProt | Q10651 (A4_CAEEL) |
| Relationships |
Total Number of functionally related compound(s) :
8
Total Number of Articles : 7 |
Description |
Amyloid-beta-like protein |
| Gene Summary |
Predicted to enable heparin binding activity and transition metal ion binding activity. Involved in body morphogenesis; ecdysis, collagen and cuticulin-based cuticle; and nematode larval development. Located in cytoplasmic vesicle; neuron projection; and neuronal cell body. Is expressed in several structures, including epithelial cell; excretory cell; hermaphrodite gonad; neurons; and pharyngeal-intestinal valve. Used to study Alzheimer's disease. Human ortholog(s) of this gene implicated in APP-related cerebral amyloid angiopathy; Alzheimer's disease; Alzheimer's disease 1; cognitive disorder; and visual epilepsy. Orthologous to several human genes including APLP1 (amyloid beta precursor like protein 1) and APLP2 (amyloid beta precursor like protein 2). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |