Protein Name LIM homeobox protein 2
Organism Mus musculus
Gene ID 16870
Gene Symbol

Lhx2

UniProt Q9Z0S2 (LHX2_MOUSE), F6Z9H5 (F6Z9H5_MOUSE), Q543C6 (Q543C6_MOUSE)
Relationships Total Number of functionally related compound(s) : 85
Total Number of Articles : 72
Description

LIM homeobox protein 2

Gene Summary

Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and chromatin binding activity. Involved in several processes, including nervous system development; positive regulation of neural precursor cell proliferation; and regulation of gene expression. Acts upstream of or within several processes, including hair follicle development; maintenance of epithelial cell apical/basal polarity; and nervous system development. Located in nucleus. Is expressed in several structures, including branchial arch; future brain; limb primordium; nervous system; and sensory organ. Orthologous to human LHX2 (LIM homeobox 2). [provided by Alliance of Genome Resources, Apr 2025]

synonyms
  • LIM/homeobox protein Lhx2
  • LIM homeo box protein 2
  • homeobox protein LH-2
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Properties