Protein Name calnexin
Organism Homo sapiens
Gene ID 821
Gene Symbol

CANX

UniProt P27824 (CALX_HUMAN)
Relationships Total Number of functionally related compound(s) : 197
Total Number of Articles : 288
Description

calnexin

Gene Summary

This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2018]

synonyms
  • calnexin
  • epididymis secretory sperm binding protein
  • major histocompatibility complex class I antigen-binding protein p88
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Properties