Protein Name histone deacetylase 7
Organism Homo sapiens
Gene ID 51564
Gene Symbol

HDAC7

UniProt Q8WUI4 (HDAC7_HUMAN)
Relationships Total Number of functionally related compound(s) : 69
Total Number of Articles : 67
Description

histone deacetylase 7

Gene Summary

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • histone deacetylase 7
  • histone deacetylase 7A
  • protein deacetylase HDAC7
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Properties