| Protein Name | toll-like receptor 2 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 24088 |
| Gene Symbol | Tlr2 |
| UniProt | Q9QUN7 (TLR2_MOUSE), G3X8Y8 (G3X8Y8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
560
Total Number of Articles : 802 |
Description |
toll-like receptor 2 |
| Gene Summary |
Enables several functions, including amyloid-beta binding activity; lipopeptide binding activity; and lipoteichoic acid binding activity. Involved in several processes, including microglia development; negative regulation of cellular component organization; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within several processes, including positive regulation of defense response; regulation of cytokine production; and response to bacterium. Located in external side of plasma membrane. Part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Is expressed in several structures, including brain; early embryo; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |