Protein Name toll-like receptor 2
Organism Mus musculus
Gene ID 24088
Gene Symbol

Tlr2

UniProt Q9QUN7 (TLR2_MOUSE), G3X8Y8 (G3X8Y8_MOUSE)
Relationships Total Number of functionally related compound(s) : 560
Total Number of Articles : 802
Description

toll-like receptor 2

Gene Summary

Enables lipoteichoic acid binding activity and peptide binding activity. Involved in several processes, including negative regulation of cellular component organization; positive regulation of cytokine production; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within several processes, including pattern recognition receptor signaling pathway; regulation of cytokine production; and response to bacterium. Located in external side of plasma membrane. Part of Toll-like receptor 2-Toll-like receptor 6 protein complex. Is expressed in several structures, including brain; early embryo; genitourinary system; gut; and immune system. Human ortholog(s) of this gene implicated in several diseases, including autoimmune disease (multiple); dermatitis (multiple); gastrointestinal system cancer (multiple); lung disease (multiple); and rhinitis (multiple). Orthologous to human TLR2 (toll like receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • toll-like receptor 2
  • Ly105
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Properties