Protein Name scavenger receptor class B, member 1
Organism Mus musculus
Gene ID 20778
Gene Symbol

Scarb1

UniProt Q61009 (SCRB1_MOUSE)
Relationships Total Number of functionally related compound(s) : 213
Total Number of Articles : 404
Description

scavenger receptor class B, member 1

Gene Summary

Enables amyloid-beta binding activity; apolipoprotein binding activity; and high-density lipoprotein particle binding activity. Involved in several processes, including lipid homeostasis; lipid transport; and regulation of lipid metabolic process. Acts upstream of or within several processes, including blood vessel endothelial cell migration; cholesterol catabolic process; and endothelial cell proliferation. Located in caveola; cell surface; and cytoplasm. Is integral component of plasma membrane. Is expressed in several structures, including alimentary system; brain; extraembryonic component; hemolymphoid system gland; and reproductive system. Orthologous to human SCARB1 (scavenger receptor class B member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • scavenger receptor class B member 1
  • HDL QTL 1
  • scavenger receptor class B type I
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Properties