Protein Name complement component 1, s subcomponent 1
Organism Mus musculus
Gene ID 50908
Gene Symbol

C1s1

UniProt Q8CG14 (CS1A_MOUSE), E9Q6C2 (E9Q6C2_MOUSE), Q14DT6 (Q14DT6_MOUSE)
Relationships Total Number of functionally related compound(s) : 78
Total Number of Articles : 61
Description

complement component 1, s subcomponent 1

Gene Summary

Predicted to enable identical protein binding activity and serine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to act upstream of or within complement activation, classical pathway and innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in chondrocranium; liver lobe; renal calyx; and urogenital ridge. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome periodontal type 2. Orthologous to human C1S (complement C1s). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • complement C1s-1 subcomponent
  • C1 esterase
  • complement C1s-A subcomponent
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Properties