| Protein Name | transient receptor potential cation channel subfamily V member 6 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 55503 |
| Gene Symbol | TRPV6 |
| UniProt | Q9H1D0 (TRPV6_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
137
Total Number of Articles : 170 |
Description |
transient receptor potential cation channel subfamily V member 6 |
| Gene Summary |
This gene encodes a member of a family of multipass membrane proteins that functions as calcium channels. The encoded protein contains N-terminal ankyrin repeats, which are required for channel assembly and regulation. Translation initiation for this protein occurs at a non-AUG start codon that is decoded as methionine. This gene is situated next to a closely related gene for transient receptor potential cation channel subfamily V member 5 (TRPV5). This locus has experienced positive selection in non-African populations, resulting in several non-synonymous codon differences among individuals of different genetic backgrounds. [provided by RefSeq, Feb 2015] |
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