| Protein Name | PTEN induced putative kinase 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 68943 |
| Gene Symbol | Pink1 |
| UniProt | Q99MQ3 (PINK1_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
163
Total Number of Articles : 190 |
Description |
PTEN induced putative kinase 1 |
| Gene Summary |
Enables ATP binding activity; magnesium ion binding activity; and protein kinase activity. Involved in several processes, including negative regulation of apoptotic process; protein stabilization; and regulation of gene expression. Acts upstream of or within positive regulation of dopamine secretion; positive regulation of dopaminergic synaptic transmission; and positive regulation of mitochondrial electron transport, NADH to ubiquinone. Located in endoplasmic reticulum and mitochondrial inner membrane. Is expressed in several structures, including alimentary system; cardiovascular system; central nervous system; genitourinary system; and sensory organ. Used to study Parkinson's disease 6. Human ortholog(s) of this gene implicated in Parkinson's disease and Parkinson's disease 6. Orthologous to human PINK1 (PTEN induced kinase 1). [provided by Alliance of Genome Resources, Jul 2025] |
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