Protein Name heat shock protein family B (small) member 1
Organism Rattus norvegicus
Gene ID 24471
Gene Symbol

Hspb1

UniProt G3V913 (G3V913_RAT)
Relationships Total Number of functionally related compound(s) : 250
Total Number of Articles : 250
Description

heat shock protein family B (small) member 1

Gene Summary

Enables ubiquitin binding activity. Involved in several processes, including cellular response to butyrate; cellular response to interleukin-11; and response to ischemia. Located in several cellular components, including myofibril; perikaryon; and postsynaptic density membrane. Part of proteasome complex. Biomarker of Alzheimer's disease and transient cerebral ischemia. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease axonal type 2F; autosomal dominant distal hereditary motor neuronopathy 3; pancreatic cancer; and sarcoma. Orthologous to human HSPB1 (heat shock protein family B (small) member 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • heat shock protein beta-1
  • HSP 27
  • heat shock 27 kDa protein 1
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Properties