CPRiL

WASF3

WASP family member 3

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. A pseudogene of this gene have been defined on chromosome 6. Alternative splicing results in multiple transcript variants [provided by RefSeq, May 2014]

• actin-binding protein WASF3
• WAS protein family member 3
• WASP family Verprolin-homologous protein 3
protein WAVE-3
verprolin homology domain-containing protein 3
wiskott-Aldrich syndrome protein family member 3
Brush-1
SCAR3
WAVE3