Protein Name transient receptor potential cation channel, subfamily A, member 1
Organism Rattus norvegicus
Gene ID 312896
Gene Symbol

Trpa1

UniProt Q6RI86 (TRPA1_RAT)
Relationships Total Number of functionally related compound(s) : 238
Total Number of Articles : 272
Description

transient receptor potential cation channel, subfamily A, member 1

Gene Summary

Enables osmolarity-sensing cation channel activity and voltage-gated calcium channel activity. Involved in several processes, including cellular response to caffeine; positive regulation of transport; and regulation of nervous system process. Located in apical plasma membrane and axon. Used to study asthma and diabetic neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • transient receptor potential cation channel subfamily A member 1
  • ankyrin-like with transmembrane domains protein 1
  • wasabi receptor
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Properties