Protein Name ATP binding cassette subfamily B member 8
Organism Homo sapiens
Gene ID 11194
Gene Symbol

ABCB8

UniProt Q9NUT2 (MITOS_HUMAN)
Relationships Total Number of functionally related compound(s) : 17
Total Number of Articles : 10
Description

ATP binding cassette subfamily B member 8

Gene Summary

This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

synonyms
  • mitochondrial potassium channel ATP-binding subunit
  • ATP-binding cassette sub-family B member 8, mitochondrial
  • ATP-binding cassette, sub-family B (MDR/TAP), member 8
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Properties