Protein Name | ATP binding cassette subfamily B member 8 |
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Organism | Homo sapiens |
Gene ID | 11194 |
Gene Symbol | ABCB8 |
UniProt | Q9NUT2 (MITOS_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
17
Total Number of Articles : 10 |
Description |
ATP binding cassette subfamily B member 8 |
Gene Summary |
This nuclear gene encodes a multi-pass membrane protein that is targeted to the mitochondrial inner membrane. The encoded protein is an ATP-dependent transporter that may mediate the passage of organic and inorganic molecules out of the mitochondria. Loss of function of the related gene in mouse results in a disruption of iron homeostasis between the mitochondria and cytosol. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
synonyms |
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Properties | |