Protein Name polo like kinase 4
Organism Homo sapiens
Gene ID 10733
Gene Symbol

PLK4

UniProt O00444 (PLK4_HUMAN)
Relationships Total Number of functionally related compound(s) : 59
Total Number of Articles : 62
Description

polo like kinase 4

Gene Summary

This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle. Three alternatively spliced transcript variants that encode different protein isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

synonyms
  • serine/threonine-protein kinase PLK4
  • Snk akin kinase
  • serine/threonine-protein kinase 18
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Properties