Protein Name cytochrome P450, family 19, subfamily A, polypeptide 1b
Organism Danio rerio
Gene ID 60640
Gene Symbol

cyp19a1b

UniProt Q5U870 (Q5U870_DANRE)
Relationships Total Number of functionally related compound(s) : 46
Total Number of Articles : 43
Description

cytochrome P450, family 19, subfamily A, polypeptide 1b

Gene Summary

Predicted to enable several functions, including heme binding activity; iron ion binding activity; and monooxygenase activity. Acts upstream of or within several processes, including response to estradiol; response to estrogen; and response to steroid hormone. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including brain; cranial nerve; gonad; head; and radial glial cell. Human ortholog(s) of this gene implicated in several diseases, including aromatase excess syndrome; bladder neck obstruction; esophagus adenocarcinoma; ovarian disease (multiple); and prostate disease (multiple). Orthologous to human CYP19A1 (cytochrome P450 family 19 subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • cytochrome P450 19A1B
  • cytochrome P450, family 19, subfamily A, polypeptide 1b
  • aromatase B
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Properties