| Protein Name | bone morphogenetic protein 7 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 12162 |
| Gene Symbol | Bmp7 |
| UniProt | P23359 (BMP7_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
105
Total Number of Articles : 94 |
Description |
bone morphogenetic protein 7 |
| Gene Summary |
This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. Mutation of this gene results in skeletal, kidney, and other developmental defects. [provided by RefSeq, Jul 2016] |
| synonyms |
|
| Properties | |