| Protein Name | desmoglein 2 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 1829 |
| Gene Symbol | DSG2 |
| UniProt | Q14126 (DSG2_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
44
Total Number of Articles : 39 |
Description |
desmoglein 2 |
| Gene Summary |
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. [provided by RefSeq, Jan 2016] |
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| Properties | |