| Protein Name | nuclear receptor subfamily 1, group H, member 3 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 58852 |
| Gene Symbol | Nr1h3 |
| UniProt | Q5I035 (Q5I035_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
91
Total Number of Articles : 97 |
Description |
nuclear receptor subfamily 1, group H, member 3 |
| Gene Summary |
Enables nuclear retinoid X receptor binding activity and sequence-specific DNA binding activity. Involved in several processes, including hematopoietic or lymphoid organ development; insulin receptor signaling pathway; and response to cholesterol. Located in nucleolus. Used to study metabolic dysfunction and alcohol associated liver disease. Biomarker of metabolic dysfunction and alcohol associated liver disease and obesity. Human ortholog(s) of this gene implicated in cerebral infarction; cerebrovascular disease; myocardial infarction; and obesity. Orthologous to human NR1H3 (nuclear receptor subfamily 1 group H member 3). [provided by Alliance of Genome Resources, Jul 2025] |
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