Protein Name trefoil factor 2 (spasmolytic protein 1)
Organism Mus musculus
Gene ID 21785
Gene Symbol

Tff2

UniProt Q9QX97 (Q9QX97_MOUSE)
Relationships Total Number of functionally related compound(s) : 46
Total Number of Articles : 39
Description

trefoil factor 2 (spasmolytic protein 1)

Gene Summary

Enables CXCR4 chemokine receptor binding activity. Acts upstream of or within several processes, including negative regulation of gastric acid secretion; negative regulation of macrophage activation; and positive regulation of ERK1 and ERK2 cascade. Located in extracellular space. Is expressed in several structures, including alimentary system; genitourinary system; liver; skeleton; and thymus. Orthologous to human TFF2 (trefoil factor 2). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • trefoil factor 2
  • spasmolytic polypeptide
  • SP
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Properties