Protein Name ubiquitin C-terminal hydrolase L1
Organism Homo sapiens
Gene ID 7345
Gene Symbol

UCHL1

UniProt P09936 (UCHL1_HUMAN), V9HW74 (V9HW74_HUMAN)
Relationships Total Number of functionally related compound(s) : 185
Total Number of Articles : 166
Description

ubiquitin C-terminal hydrolase L1

Gene Summary

The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]

synonyms
  • ubiquitin carboxyl-terminal hydrolase isozyme L1
  • epididymis luminal protein 117
  • epididymis secretory protein Li 53
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Properties