Protein Name solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
Organism Mus musculus
Gene ID 26570
Gene Symbol

Slc7a11

UniProt Q9WTR6 (XCT_MOUSE), Q542C8 (Q542C8_MOUSE)
Relationships Total Number of functionally related compound(s) : 153
Total Number of Articles : 206
Description

solute carrier family 7 (cationic amino acid transporter, y+ system), member 11

Gene Summary

Predicted to enable L-kynurenine transmembrane transporter activity and cystine:glutamate antiporter activity. Involved in L-cystine transport. Acts upstream of or within several processes, including oligopeptide transmembrane transport; regulation of amino acid metabolic process; and regulation of protein localization. Located in astrocyte projection and brush border membrane. Is expressed in brain; eye; olfactory epithelium; and spinal cord meninges. Used to study Hermansky-Pudlak syndrome and platelet storage pool deficiency. Orthologous to human SLC7A11 (solute carrier family 7 member 11). [provided by Alliance of Genome Resources, Jun 2025]

synonyms
  • cystine/glutamate transporter
  • amino acid transport system xc-
  • cysteine/glutamate transporter
Click to show/hide the synonyms
Properties