| Protein Name | solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20512 |
| Gene Symbol | Slc1a3 |
| UniProt | P56564 (EAA1_MOUSE), Q543U3 (Q543U3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
127
Total Number of Articles : 178 |
Description |
solute carrier family 1 (glial high affinity glutamate transporter), member 3 |
| Gene Summary |
Enables glutamate binding activity and high-affinity L-glutamate transmembrane transporter activity. Involved in D-aspartate import across plasma membrane and cellular response to cocaine. Acts upstream of or within several processes, including L-glutamate import across plasma membrane; gamma-aminobutyric acid biosynthetic process; and nervous system development. Located in several cellular components, including cell surface; neuron projection; and neuronal cell body. Is expressed in several structures, including central nervous system; connective tissue; eye; foregut; and genitourinary system. Used to study low tension glaucoma. Human ortholog(s) of this gene implicated in episodic ataxia type 6. Orthologous to human SLC1A3 (solute carrier family 1 member 3). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |