Protein Name annexin 1
Organism Arabidopsis thaliana
Gene ID 840476
Gene Symbol

ANNAT1

UniProt Q9SYT0 (ANXD1_ARATH), A0A178WGZ8 (A0A178WGZ8_ARATH)
Relationships Total Number of functionally related compound(s) : 29
Total Number of Articles : 30
Description

annexin 1

Gene Summary

Encodes a member of the annexin gene family, a diverse, multigene family of calcium-dependent, membrane-binding proteins. The protein was determined to have peroxidase activity. This activity is thought to be dependent on the presence of post-translational modifications (most likely phosphorylation). The protein was shown to be present as a mixture of monomer and homodimer. The homodimerization seems to be dependent on the presence of Ca2+ or H2O2. The dimerization was prevented by the addition of DTT, beta-mercaptoethanol and TCEP. Annat1 mRNA is expressed in flowers, roots,leaves and stems and is most abundant in stems. mRNA levels are increased in response to oxidative stress. Developmental expression patterns suggest a role in Golgi-mediated polysaccharide secretion. It is a Ca 2+-permeable transporter providing a molecular link between reactive oxygen species and cytosolic Ca 2+ in plants.

synonyms
  • annexin 1
  • AT1G35720
  • ANN1
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Properties