Protein Name Parkinsonism associated deglycase
Organism Homo sapiens
Gene ID 11315
Gene Symbol

PARK7

UniProt Q99497 (PARK7_HUMAN), V9HWC2 (V9HWC2_HUMAN)
Relationships Total Number of functionally related compound(s) : 275
Total Number of Articles : 368
Description

Parkinsonism associated deglycase

Gene Summary

The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008]

synonyms
  • Parkinson disease protein 7
  • Parkinson disease (autosomal recessive, early onset) 7
  • epididymis secretory sperm binding protein Li 67p
Click to show/hide the synonyms
Properties