Protein Name | Parkinsonism associated deglycase |
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Organism | Homo sapiens |
Gene ID | 11315 |
Gene Symbol | PARK7 |
UniProt | Q99497 (PARK7_HUMAN), V9HWC2 (V9HWC2_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
275
Total Number of Articles : 368 |
Description |
Parkinsonism associated deglycase |
Gene Summary |
The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Jul 2008] |
synonyms |
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Properties | |