| Protein Name | interleukin 17A |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 301289 |
| Gene Symbol | Il17a |
| UniProt | G3V7M4 (G3V7M4_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
290
Total Number of Articles : 319 |
Description |
interleukin 17A |
| Gene Summary |
Predicted to enable cytokine activity; protein heterodimerization activity; and protein homodimerization activity. Involved in cellular response to glucocorticoid stimulus; positive regulation of transcription by RNA polymerase II; and response to amino acid. Located in extracellular space. Used to study anti-basement membrane glomerulonephritis; congestive heart failure; myocarditis; pleurisy; and uveitis. Biomarker of several diseases, including acute necrotizing pancreatitis; inflammatory bowel disease (multiple); lung disease (multiple); myocardial infarction (multiple); and periodontal disease (multiple). Human ortholog(s) of this gene implicated in Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); macular degeneration; and rhinitis (multiple). Orthologous to human IL17A (interleukin 17A). [provided by Alliance of Genome Resources, Jun 2025] |
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