Protein Name interleukin 17A
Organism Rattus norvegicus
Gene ID 301289
Gene Symbol

Il17a

UniProt G3V7M4 (G3V7M4_RAT)
Relationships Total Number of functionally related compound(s) : 290
Total Number of Articles : 319
Description

interleukin 17A

Gene Summary

Predicted to enable protein heterodimerization activity and protein homodimerization activity. Involved in several processes, including cellular response to glucocorticoid stimulus; positive regulation of necrotic cell death; and positive regulation of transcription by RNA polymerase II. Located in cytoplasm and extracellular space. Used to study anti-basement membrane glomerulonephritis; congestive heart failure; myocarditis; pleurisy; and uveitis. Biomarker of several diseases, including acute necrotizing pancreatitis; inflammatory bowel disease (multiple); lipoid nephrosis; lung disease (multiple); and periodontal disease (multiple). Human ortholog(s) of this gene implicated in Mycobacterium avium complex disease; autoimmune disease (multiple); bronchial disease (multiple); macular degeneration; and rhinitis (multiple). Orthologous to human IL17A (interleukin 17A). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • interleukin-17A
  • Interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
  • cytotoxic T-lymphocyte-associated antigen 8
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Properties