| Protein Name | myocardin related transcription factor A |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 315151 |
| Gene Symbol | Mrtfa |
| UniProt | A0A0G2K3Y9 (A0A0G2K3Y9_RAT), F1LV40 (F1LV40_RAT), A0A0G2JXC5 (A0A0G2JXC5_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
12
Total Number of Articles : 12 |
Description |
myocardin related transcription factor A |
| Gene Summary |
Predicted to enable several functions, including actin monomer binding activity; leucine zipper domain binding activity; and transcription coactivator activity. Involved in several processes, including negative regulation of apoptotic process; positive regulation of cell differentiation; and positive regulation of collagen biosynthetic process. Located in cytosol and nucleus. Is active in glutamatergic synapse; postsynapse; and presynapse. Biomarker of Alzheimer's disease and transient cerebral ischemia. Human ortholog(s) of this gene implicated in acute megakaryocytic leukemia and immunodeficiency 66. Orthologous to human MRTFA (myocardin related transcription factor A). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |