Protein Name phospholipase D2
Organism Homo sapiens
Gene ID 5338
Gene Symbol

PLD2

UniProt O14939 (PLD2_HUMAN)
Relationships Total Number of functionally related compound(s) : 180
Total Number of Articles : 177
Description

phospholipase D2

Gene Summary

The protein encoded by this gene catalyzes the hydrolysis of phosphatidylcholine to phosphatidic acid and choline. The activity of the encoded enzyme is enhanced by phosphatidylinositol 4,5-bisphosphate and ADP-ribosylation factor-1. This protein localizes to the peripheral membrane and may be involved in cytoskeletal organization, cell cycle control, transcriptional regulation, and/or regulated secretion. Two transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

synonyms
  • phospholipase D2
  • choline phosphatase 2
  • phosphatidylcholine-hydrolyzing phospholipase D2
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Properties