| Protein Name | triggering receptor expressed on myeloid cells 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 54210 |
| Gene Symbol | TREM1 |
| UniProt | Q9NP99 (TREM1_HUMAN), Q38L15 (Q38L15_HUMAN), K7EKM5 (K7EKM5_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
60
Total Number of Articles : 69 |
Description |
triggering receptor expressed on myeloid cells 1 |
| Gene Summary |
This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011] |
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