| Protein Name | autophagy related 5 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 365601 |
| Gene Symbol | Atg5 |
| UniProt | Q5XIS0 (Q5XIS0_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
99
Total Number of Articles : 98 |
Description |
autophagy related 5 |
| Gene Summary |
Predicted to contribute to Atg8-family ligase activity. Involved in several processes, including chaperone-mediated autophagy; positive regulation of stress granule assembly; and response to iron(II) ion. Located in axon. Part of protein-containing complex. Is active in glutamatergic synapse. Biomarker of ischemia and metabolic dysfunction-associated steatohepatitis. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 25. Orthologous to human ATG5 (autophagy related 5). [provided by Alliance of Genome Resources, Jun 2025] |
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| Properties | |