Protein Name ribosomal protein S4 X-linked
Organism Homo sapiens
Gene ID 6191
Gene Symbol

RPS4X

UniProt P62701 (RS4X_HUMAN), B2R491 (B2R491_HUMAN)
Relationships Total Number of functionally related compound(s) : 47
Total Number of Articles : 45
Description

ribosomal protein S4 X-linked

Gene Summary

Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

synonyms
  • small ribosomal subunit protein eS4, X isoform
  • 40S ribosomal protein S4
  • cell cycle gene 2
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Properties