CPRiL

MALAT1

metastasis associated lung adenocarcinoma transcript 1

This gene produces a precursor transcript from which a long non-coding RNA is derived by RNase P cleavage of a tRNA-like small ncRNA (known as mascRNA) from its 3' end. The resultant mature transcript lacks a canonical poly(A) tail but is instead stabilized by a 3' triple helical structure. This transcript is retained in the nucleus where it is thought to form molecular scaffolds for ribonucleoprotein complexes. It may act as a transcriptional regulator for numerous genes, including some genes involved in cancer metastasis and cell migration, and it is involved in cell cycle regulation. Its upregulation in multiple cancerous tissues has been associated with the proliferation and metastasis of tumor cells. [provided by RefSeq, Mar 2015]

• hepcarcin
• long intergenic non-protein coding RNA 47
• metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
nuclear enriched abundant transcript 2
nuclear paraspeckle assembly transcript 2 (non-protein coding)
HCN
LINC00047
NCRNA00047
NEAT2
PRO2853