| Protein Name | uncoupling protein 2 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 54315 |
| Gene Symbol | Ucp2 |
| UniProt | P56500 (UCP2_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
182
Total Number of Articles : 250 |
Description |
uncoupling protein 2 |
| Gene Summary |
Predicted to enable oxidative phosphorylation uncoupler activity. Involved in several processes, including cellular response to glucose stimulus; liver regeneration; and negative regulation of insulin secretion involved in cellular response to glucose stimulus. Located in mitochondrion. Used to study hypertension; non-alcoholic fatty liver disease; transient cerebral ischemia; and type 2 diabetes mellitus. Biomarker of congestive heart failure; fatty liver disease (multiple); hypothyroidism; obstructive jaundice; and type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in carotid artery disease; diabetic neuropathy; end stage renal disease; hypertension; and obesity. Orthologous to human UCP2 (uncoupling protein 2). [provided by Alliance of Genome Resources, Apr 2022] |
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| Properties | |