| Protein Name | 5-hydroxytryptamine receptor 2B |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 3357 |
| Gene Symbol | HTR2B |
| UniProt | P41595 (5HT2B_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
168
Total Number of Articles : 170 |
Description |
5-hydroxytryptamine receptor 2B |
| Gene Summary |
This gene encodes one of the several different receptors for 5-hydroxytryptamine (serotonin) that belongs to the G-protein coupled receptor 1 family. Serotonin is a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. Serotonin receptors mediate many of the central and peripheral physiologic functions of serotonin, including regulation of cardiovascular functions and impulsive behavior. Population and family-based analyses of a minor allele (glutamine-to-stop substitution, designated Q20*) which blocks expression of this protein, and knockout studies in mice, suggest a role for this gene in impulsivity. However, other factors, such as elevated testosterone levels, may also be involved. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016] |
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