Protein Name Mediator of RNA polymerase II transcription subunit 15
Organism Caenorhabditis elegans
Gene ID 175817
Gene Symbol

mdt-15

UniProt Q21955 (MED15_CAEEL)
Relationships Total Number of functionally related compound(s) : 22
Total Number of Articles : 21
Description

Mediator of RNA polymerase II transcription subunit 15

Gene Summary

Enables nuclear receptor binding activity and transcription coactivator activity. Involved in several processes, including determination of adult lifespan; nematode larval development; and sequestering of triglyceride. Predicted to be located in nucleus. Predicted to be part of mediator complex. Is expressed in several structures, including excretory gland cell; hermaphrodite gonad; intestine; nervous system; and rectal gland cell. Used to study chromosome 22q11.2 deletion syndrome, distal. Human ortholog(s) of this gene implicated in schizophrenia. Orthologous to human MED15 (mediator complex subunit 15). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • Mediator of RNA polymerase II transcription subunit 15
  • CELE_R12B2.5
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Properties