| Protein Name | B cell scaffold protein with ankyrin repeats 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 55024 |
| Gene Symbol | BANK1 |
| UniProt | Q8NDB2 (BANK1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
34
Total Number of Articles : 32 |
Description |
B cell scaffold protein with ankyrin repeats 1 |
| Gene Summary |
The protein encoded by this gene is a B-cell-specific scaffold protein that functions in B-cell receptor-induced calcium mobilization from intracellular stores. This protein can also promote Lyn-mediated tyrosine phosphorylation of inositol 1,4,5-trisphosphate receptors. Polymorphisms in this gene are associated with susceptibility to systemic lupus erythematosus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009] |
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