Protein Name nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
Organism Mus musculus
Gene ID 18018
Gene Symbol

Nfatc1

UniProt B5B2N4 (B5B2N4_MOUSE), Q6P7T9 (Q6P7T9_MOUSE), B5B2N5 (B5B2N5_MOUSE), Q9DBQ6 (Q9DBQ6_MOUSE), B5B2N2 (B5B2N2_MOUSE), B5B2N7 (B5B2N7_MOUSE)
Relationships Total Number of functionally related compound(s) : 324
Total Number of Articles : 369
Description

nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Gene Summary

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and mitogen-activated protein kinase p38 binding activity. Involved in heart development and positive regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including animal organ development; branching involved in lymph vessel morphogenesis; and regulation of gene expression. Located in cytoplasm and nucleus. Part of transcription regulator complex. Is expressed in several structures, including alimentary system; early conceptus; eye; genitourinary system; and heart. Orthologous to human NFATC1 (nuclear factor of activated T cells 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • nuclear factor of activated T-cells, cytoplasmic 1
  • NF-ATc1
  • NFAT transcription complex cytosolic component
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Properties