Protein Name oxidized low density lipoprotein receptor 1
Organism Homo sapiens
Gene ID 4973
Gene Symbol

OLR1

UniProt P78380 (OLR1_HUMAN), A0A024RAU0 (A0A024RAU0_HUMAN)
Relationships Total Number of functionally related compound(s) : 266
Total Number of Articles : 298
Description

oxidized low density lipoprotein receptor 1

Gene Summary

This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer's disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]

synonyms
  • oxidized low-density lipoprotein receptor 1
  • C-type lectin domain family 8 member A
  • hLOX-1
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Properties