Protein Name ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3
Organism Homo sapiens
Gene ID 489
Gene Symbol

ATP2A3

UniProt Q93084 (AT2A3_HUMAN), A8K9K1 (A8K9K1_HUMAN)
Relationships Total Number of functionally related compound(s) : 123
Total Number of Articles : 160
Description

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3

Gene Summary

This gene encodes one of the SERCA Ca(2+)-ATPases, which are intracellular pumps located in the sarcoplasmic or endoplasmic reticula of muscle cells. This enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen, and is involved in calcium sequestration associated with muscular excitation and contraction. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

synonyms
  • sarcoplasmic/endoplasmic reticulum calcium ATPase 3
  • ATPase, Ca(2+)-transporting, ubiquitous
  • ATPase, Ca++ transporting, ubiquitous
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Properties