| Protein Name | thioredoxin interacting protein |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 10628 |
| Gene Symbol | TXNIP |
| UniProt | Q9H3M7 (TXNIP_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
268
Total Number of Articles : 372 |
Description |
thioredoxin interacting protein |
| Gene Summary |
This gene encodes a thioredoxin-binding protein that is a member of the alpha arrestin protein family. Thioredoxin is a thiol-oxidoreductase that is a major regulator of cellular redox signaling which protects cells from oxidative stress. This protein inhibits the antioxidative function of thioredoxin resulting in the accumulation of reactive oxygen species and cellular stress. This protein also functions as a regulator of cellular metabolism and of endoplasmic reticulum (ER) stress. This protein may also function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015] |
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| Properties | |