Protein Name calcium channel, voltage-dependent, N type, alpha 1B subunit
Organism Mus musculus
Gene ID 12287
Gene Symbol

Cacna1b

UniProt O55017 (CAC1B_MOUSE), A2AIR9 (A2AIR9_MOUSE), A2AIS0 (A2AIS0_MOUSE)
Relationships Total Number of functionally related compound(s) : 69
Total Number of Articles : 89
Description

calcium channel, voltage-dependent, N type, alpha 1B subunit

Gene Summary

Enables high voltage-gated calcium channel activity. Acts upstream of or within several processes, including calcium ion transmembrane transport; neurotransmitter secretion; and response to pain. Located in dendrite; membrane; and neuronal cell body. Part of voltage-gated calcium channel complex. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and retina. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome and dystonia 23. Orthologous to human CACNA1B (calcium voltage-gated channel subunit alpha1 B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • voltage-dependent N-type calcium channel subunit alpha-1B
  • brain calcium channel III
  • calcium channel, L type, alpha-1 polypeptide
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Properties