Protein Name | calcium channel, voltage-dependent, N type, alpha 1B subunit |
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Organism | Mus musculus |
Gene ID | 12287 |
Gene Symbol | Cacna1b |
UniProt | O55017 (CAC1B_MOUSE), A2AIR9 (A2AIR9_MOUSE), A2AIS0 (A2AIS0_MOUSE) |
Relationships |
Total Number of functionally related compound(s) :
69
Total Number of Articles : 89 |
Description |
calcium channel, voltage-dependent, N type, alpha 1B subunit |
Gene Summary |
Enables high voltage-gated calcium channel activity. Acts upstream of or within several processes, including calcium ion transmembrane transport; neurotransmitter secretion; and response to pain. Located in dendrite; membrane; and neuronal cell body. Part of voltage-gated calcium channel complex. Is expressed in several structures, including adrenal gland; alimentary system; brain; genitourinary system; and retina. Human ortholog(s) of this gene implicated in Lambert-Eaton myasthenic syndrome and dystonia 23. Orthologous to human CACNA1B (calcium voltage-gated channel subunit alpha1 B). [provided by Alliance of Genome Resources, Apr 2022] |
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Properties | |