Protein Name | phosphofructokinase, platelet |
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Organism | Homo sapiens |
Gene ID | 5214 |
Gene Symbol | PFKP |
UniProt | Q01813 (PFKAP_HUMAN), A0A7I2V3Z0 (A0A7I2V3Z0_HUMAN), B1APP6 (B1APP6_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
32
Total Number of Articles : 29 |
Description |
phosphofructokinase, platelet |
Gene Summary |
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016] |
synonyms |
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Properties | |