Protein Name phosphofructokinase, platelet
Organism Homo sapiens
Gene ID 5214
Gene Symbol

PFKP

UniProt Q01813 (PFKAP_HUMAN), A0A7I2V3Z0 (A0A7I2V3Z0_HUMAN), B1APP6 (B1APP6_HUMAN)
Relationships Total Number of functionally related compound(s) : 32
Total Number of Articles : 29
Description

phosphofructokinase, platelet

Gene Summary

This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]

synonyms
  • ATP-dependent 6-phosphofructokinase, platelet type
  • 6-phosphofructokinase type C
  • 6-phosphofructokinase, platelet type
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Properties