Protein Name selectin L
Organism Homo sapiens
Gene ID 6402
Gene Symbol


UniProt P14151 (LYAM1_HUMAN)
Relationships Total Number of functionally related compound(s) : 565
Total Number of Articles : 660

selectin L

Gene Summary

This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009]

  • L-selectin
  • CD62 antigen-like family member L
  • gp90-MEL
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