| Protein Name | selectin L |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6402 |
| Gene Symbol | SELL |
| UniProt | P14151 (LYAM1_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
565
Total Number of Articles : 660 |
Description |
selectin L |
| Gene Summary |
This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2009] |
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