Protein Name outer dense fiber of sperm tails 1
Organism Homo sapiens
Gene ID 4956
Gene Symbol

ODF1

UniProt Q14990 (ODFP1_HUMAN)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 27
Description

outer dense fiber of sperm tails 1

Gene Summary

The outer dense fibers are cytoskeletal structures that surround the axoneme in the middle piece and principal piece of the sperm tail. The fibers function in maintaining the elastic structure and recoil of the sperm tail as well as in protecting the tail from shear forces during epididymal transport and ejaculation. Defects in the outer dense fibers lead to abnormal sperm morphology and infertility. The human outer dense fibers contains at least 10 major proteins and this gene encodes the main protein. [provided by RefSeq, Jul 2008]

synonyms
  • outer dense fiber protein 1
  • cancer/testis antigen 133
  • heat shock protein beta-10
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Properties